The minor allele of ANGPTL8 rs2278426 has a protective effect against CAD in T2DM patients.

doi:10.1016/j.gene.2024.148418

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Article

The minor allele of ANGPTL8 rs2278426 has a protective effect against CAD in T2DM patients.

Gene - 1 Jul 2024

Bilgin Aslihan Gizem, Ekici Berkay, Ozuynuk-Ertugrul Aybike Sena, Erkan Aycan Fahri, Coban Neslihan

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) is the leading cause of death worldwide despite advanced treatment and diagnosis strategies. Angiopoietin-like protein 8 (ANGPTL8) mainly functions in the lipid mechanism, which is a dysregulated mechanism during CAD pathogenesis. In this study, we aimed to determine the associations between an ANGPTL8 polymorphism rs2278426 and the severity, presence, and risk factors of...

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PMID: 38552749
DOI: 10.1016/j.gene.2024.148418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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