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MicroRNA‑155‑5p inhibits trophoblast cell proliferation and invasion by disrupting centrosomal function

22 Mar 2024

Abstract excerpt

Recurrent miscarriage is used to refer to more than three pregnancy failures before 20 weeks of gestation. Defective trophoblast cell growth and invasion are frequently observed in recurrent miscarriage. Several microRNAs (miRs), including miR‑155‑5p, are aberrantly upregulated in recurrent miscarriage; however, the underlying molecular mechanisms remain unclear. The centrosome orchestrates microtubule networks...

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PMID: 38551159
DOI: 10.3892/mmr.2024.13209

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