The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis.

doi:10.3390/ijms23137396

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Article

The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis.

International journal of molecular sciences - 2 Jul 2022

Kisielnicka Anna, Sobalska-Kwapis Marta, Purzycka-Bohdan Dorota, Nedoszytko Bogusław, Zabłotna Monika, Seweryn Michał, Strapagiel Dominik, Nowicki Roman J, Reich Adam, Samotij Dominik, Szczęch Justyna, Krasowska Dorota, Bartosińska Joanna, Narbutt Joanna, Lesiak Aleksandra, Barasińska Paulina, Owczarczyk-Saczonek Agnieszka, Czerwińska Joanna, Szepietowski Jacek C, Batycka-Baran Aleksandra, Czajkowski Rafał, Górecka-Sokołowska Magdalena, Rudnicka Lidia, Czuwara Joanna, Szczerkowska-Dobosz Aneta

Abstract excerpt

There is evidence that the concomitance of psoriasis and obesity may originate from the interplay between multiple genetic pathways and involve gene−gene interactions. The aim of this study was to compare the genetic background related to obesity among psoriatic patients versus healthy controls by means of a Genome-Wide Association Study (GWAS). A total of 972 psoriatic patients and a total of 5878 healthy donors...

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PMID: 35806402
DOI: 10.3390/ijms23137396
PMCID: PMC9266424

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