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Article

Revealing the Genetic Diversity of Chinese Chlamydia trachomatis Strains Directly From Clinical Samples Through Selective Whole Genome Amplification.

The Journal of infectious diseases - 16 Oct 2024

Chen Wentao, Zhou Chuchan, Su Xin, Yin Xiaona, Yuan Weixi, Hu Chuncai, Zhao Wei

Abstract excerpt

BACKGROUND: Chlamydia trachomatis is the causative agent of the most prevalent bacterial sexually transmitted infections globally. Whole genome sequencing is essential for molecular Chlamydia surveillance; however, its application is hampered by the pathogen's low abundance in clinical specimens and the expensive labor-intensive nature of existing enrichment methodologies for Chlamydia. METHODS: We developed a...

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PMID: 38547503
DOI: 10.1093/infdis/jiae163

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