Article
Molecularly generated rat hepatitis E virus strains from human and rat show efficient replication in a human hepatoma cell line.
Virus research - 1 Jun 2024
Panajotov Jessica, Falkenhagen Alexander, Gadicherla Ashish K, Johne Reimar
Abstract excerpt
The hepatitis E virus (HEV) can cause acute and chronic hepatitis in humans. Whereas HEV genotypes 1-4 of species Paslahepevirus balayani are commonly found in humans, infections with ratHEV (species Rocahepevirus ratti) were previously considered to be restricted to rats. However, several cases of human ratHEV infections have been described recently. To investigate the zoonotic potential of this virus, a genomic...
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