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CD13 expression affects glioma patient survival and influences key functions of human glioblastoma cell lines in vitro

22 Mar 2024

Abstract excerpt

CD13 (APN) is an Alanyl-Aminopeptidase with diverse functions. The role of CD13 for gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA databases were used to evaluate the survival rate and prognostic value of CD13 expression level. Protein expression of CD13 was confirmed by immunofluorescence staining of fresh patient tissues. Eight human glioblastoma cell lines were...

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PMID: 38519889
DOI: 10.1186/s12885-024-12113-z

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