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CXCR4: from B-cell development to B cell–mediated diseases

22 Mar 2024

Abstract excerpt

Chemokine receptors are members of the G protein-coupled receptor superfamily. The C-X-C chemokine receptor type 4 (CXCR4), one of the most studied chemokine receptors, is widely expressed in hematopoietic and immune cell populations. It is involved in leukocyte trafficking in lymphoid organs and inflammatory sites through its interaction with its natural ligand CXCL12. CXCR4 assumes a pivotal role in B-cell...

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PMID: 38519141
DOI: 10.26508/lsa.202302465

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