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Article

Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma.

World journal of gastroenterology - 28 Feb 2024

Wang Yi-Ying, Shen Mei-Mei, Gao Jian

Abstract excerpt

BACKGROUND: Metadherin (MTDH) is a key oncogene in most cancer types, including hepatocellular carcinoma (HCC). Notably, MTDH does not affect the stemness pheno-type or immune infiltration of HCC. AIM: To explore the role of MTDH on stemness and immune infiltration in HCC. METHODS: MTDH expression in HCC tissues was detected using TCGA and GEO databases. Immunohistochemistry was used to analyze the tissue...

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Topics

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Share to Carcinoma, Hepatocellular
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Liver Neoplasms

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Share to RNA-Binding Proteins

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Source

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Identifiers

PMID: 38516242
DOI: 10.3748/wjg.v30.i8.901
PMCID: PMC10950638

Genes

MTDH
CD4
CX3CL1
CXCL12
CXCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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