FLRT3 and TGF ‐β/ SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia

Abstract excerpt

channels in cardiomyocytes. Bioinformatics analysis was performed on 85 SVT samples and 15 healthy controls to screen overlapping genes from the key module and differentially expressed genes (DEGs). Expression profiling of overlapping genes, coupled with Receiver Operating Characteristic (ROC) curve analyses, identified FLRT3 as a hub gene. In vitro studies utilizing Ang II-stimulated H9C2 cardiomyocytes were...

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