Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The power of representation: Statistical analysis of diversity in US Alzheimer's disease genetics data

1 Jan 2024

Abstract excerpt

INTRODUCTION: Alzheimer's disease (AD) is a complex disease influenced by genetics and environment. More than 75 susceptibility loci have been linked to late-onset AD, but most of these loci were discovered in genome-wide association studies (GWAS) exclusive to non-Hispanic White individuals. There are wide disparities in AD risk across racially stratified groups, and while these disparities are not due to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Dementia and Cognitive Impairment Research
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38500778
DOI: 10.1002/trc2.12462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The power of representation: Statistical analysis of diversity in US Alzheimer's disease genetics dataPMID 38500778Read ↗

Demographic Diversity of Genetic Databases Used in Alzheimer’s Disease ResearchSemantic proximity Read ↗

Downward bias in the association between APOE and Alzheimer’s Disease using prevalent and by-proxy disease sampling in the All of Us Research ProgramSemantic proximity Read ↗

Downward bias in the association between APOE and Alzheimer's disease using prevalent and by-proxy disease sampling in the All of Us research program.Semantic proximity Read ↗

Utilizing Electronic Medical Records Identifies Similarities and Differences in Alzheimer’s Disease Comorbidities Between Racialized PopulationsSemantic proximity Read ↗

Matching Heterogeneous Cohorts by Projected Principal Components Reveals Two Novel Alzheimer’s Disease-Associated Genes in the Hispanic PopulationSemantic proximity Read ↗

Racial and Ethnic Reporting and Representation in Phase III Alzheimer’s Disease Clinical Trials in the USSemantic proximity Read ↗

Inclusion bias affects common variant discovery and replication in a health-system linked biobankSemantic proximity Read ↗

Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.Semantic proximity Read ↗

Exploring the role of underrepresented populations in polygenic risk scores for neurodegenerative disease risk predictionSemantic proximity Read ↗

Characterizing subgroup performance of probabilistic phenotype algorithms within older adults: A case study for dementia, mild cognitive impairment, and Alzheimer’s and Parkinson’s diseasesSemantic proximity Read ↗

Curation of Mini Mental State Examination (MMSE) Scores in the VA Million Veteran Program (MVP): Applications for Cognitive Aging ResearchSemantic proximity Read ↗

Magnitude of stratification in human populations and impacts on genome wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.