Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor suppressive role of the epigenetic master regulator BRD3 in colorectal cancer

17 Mar 2024

Abstract excerpt

Bromodomain and extraterminal domain (BET) family proteins are epigenetic master regulators of gene expression via recognition of acetylated histones and recruitment of transcription factors and co-activators to chromatin. Hence, BET family proteins have emerged as promising therapeutic targets in cancer. In this study, we examined the functional role of bromodomain containing 3 (BRD3), a BET family protein, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Multiple Myeloma Research and Treatments
Share to Protein Degradation and Inhibitors
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38494600
DOI: 10.1111/cas.16129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor suppressive role of the epigenetic master regulator BRD3 in colorectal cancerPMID 38494600Read ↗

Aberrant epigenetic regulation of bromodomain Brd4 in human colon cancerSemantic proximity Read ↗

BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinomaSemantic proximity Read ↗

Bromodomain Protein BRD4-Mediated Mutant p53 Transcription Promotes TNBC ProgressionSemantic proximity Read ↗

The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesisSemantic proximity Read ↗

BRD4 and Cancer: going beyond transcriptional regulationSemantic proximity Read ↗

Bromodomain containing 4 (BRD4) as a potential prognostic marker in a pan-cancer analysis of human tumorsSemantic proximity Read ↗

Pan‐cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumoursSemantic proximity Read ↗

Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathwaySemantic proximity Read ↗

BRDT promotes ovarian cancer cell growthSemantic proximity Read ↗

BRD9 promotes the progression of gallbladder cancer via CST1 upregulation and interaction with FOXP1 through the PI3K/AKT pathway and represents a therapeutic targetSemantic proximity Read ↗

The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsSemantic proximity Read ↗

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.