Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-Validation of Metabolic Phenotypes in SARS-CoV-2 Infected Subpopulations Using Targeted Liquid Chromatography-Mass Spectrometry (LC-MS).

Journal of proteome research - 5 Apr 2024

Whiley Luke, Lawler Nathan G, Zeng Annie Xu, Lee Alex, Chin Sung-Tong, Bizkarguenaga Maider, Bruzzone Chiara, Embade Nieves, Wist Julien, Holmes Elaine, Millet Oscar, Nicholson Jeremy K, Gray Nicola

Abstract excerpt

To ensure biological validity in metabolic phenotyping, findings must be replicated in independent sample sets. Targeted workflows have long been heralded as ideal platforms for such validation due to their robust quantitative capability. We evaluated the capability of liquid chromatography-mass spectrometry (LC-MS) assays targeting organic acids and bile acids to validate metabolic phenotypes of SARS-CoV-2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Acids and Salts
Share to Chromatography, Liquid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to COVID-19

Share to Phenotype

Share to SARS-CoV-2

Share to Tandem Mass Spectrometry

Source

Open in PubMed Open full text

Identifiers

PMID: 38484742
DOI: 10.1021/acs.jproteome.3c00797
PMCID: PMC11002931

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-Validation of Metabolic Phenotypes in SARS-CoV-2 Infected Subpopulations Using Targeted Liquid Chromatography-Mass Spectrometry (LC-MS).PMID 38484742Read ↗

Diagnostic, Prognostic and Mechanistic Biomarkers of COVID-19 Identified by Mass Spectrometric MetabolomicsSemantic proximity Read ↗

Progress in understanding COVID-19: insights from the omics approachSemantic proximity Read ↗

Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics AnalysisSemantic proximity Read ↗

Excessive inflammatory and metabolic responses to acute SARS-CoV-2 infection are associated with a distinct gut microbiota compositionSemantic proximity Read ↗

Molecular Phenomic Approaches to Deconvolving the Systemic Effects of SARS-CoV-2 Infection and Post-acute COVID-19 SyndromeSemantic proximity Read ↗

Metabolic predictors of COVID-19 mortality and severity: A Survival AnalysisSemantic proximity Read ↗

The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolismSemantic proximity Read ↗

Host metabolic reprogramming in response to SARS-Cov-2 infectionSemantic proximity Read ↗

The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolismSemantic proximity Read ↗

Metabolomics analysis reveals a potential role SARS-CoV-2 viral proteins in the regulation/perturbation of metabolic pathways associated with altered plasma metabolites in COVID-19 patientsSemantic proximity Read ↗

Focusing on the metabolic changes caused by the COVID-19 disease. A Metabolomic approach using urineSemantic proximity Read ↗

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.