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Article

Short cell cycle duration is a phenotype of human epidermal stem cells.

Stem cell research & therapy - 13 Mar 2024

Xiao Tong, Eze Ugomma C, Charruyer-Reinwald Alex, Weisenberger Tracy, Khalifa Ayman, Abegaze Brook, Schwab Gabrielle K, Elsabagh Rasha H, Parenteau T Richard, Kochanowski Karl, Piper Merisa, Xia Yumin, Cheng Jeffrey B, Cho Raymond J, Ghadially Ruby

Abstract excerpt

BACKGROUND: A traditional view is that stem cells (SCs) divide slowly. Meanwhile, both embryonic and pluripotent SCs display a shorter cell cycle duration (CCD) in comparison to more committed progenitors (CPs). METHODS: We examined the in vitro proliferation and cycling behavior of somatic adult human cells using live cell imaging of passage zero keratinocytes and single-cell RNA sequencing. RESULTS: We found...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38475896
DOI: 10.1186/s13287-024-03670-y
PMCID: PMC10935907

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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