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Article

Mainstream Model of Genetic Testing for Prostate Cancer at a Large Tertiary Cancer Centre.

Clinical genitourinary cancer - 1 Jun 2024

Wang Xin, Waldman Larissa, Silberman Yael, Wang Michael, Tackey Caleb, Hanna Lilian, Vesprini Danny, Emmenegger Urban, Eisen Andrea, Smoragiewicz Martin

Abstract excerpt

BACKGROUND: An estimated 20% to 30% of men with advanced prostate cancer carry a mutation in DNA damage repair genes, of which half are estimated to be germline. Eligibility criteria for germline genetic testing expanded significantly for Ontario patients in May 2021 and many centers adopted a "mainstream" model, defined as oncologist-initiated genetic testing. METHODS: We conducted a retrospective chart review...

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Identifiers

PMID: 38461085
DOI: 10.1016/j.clgc.2024.02.003

Genes

ATM
BRCA1
BRIP1
CHEK2
HOXB13
PMS2
RAD51C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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