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Article

Spatial intratumor heterogeneity of programmed death-ligand 1 expression predicts poor prognosis in resected non–small cell lung cancer

6 Mar 2024

Abstract excerpt

BACKGROUND: We quantified the pathological spatial intratumor heterogeneity of programmed death-ligand 1 (PD-L1) expression and investigated its relevance to patient outcomes in surgically resected non-small cell lung carcinoma (NSCLC). METHODS: This study enrolled 239 consecutive surgically resected NSCLC specimens of pathological stage IIA-IIIB. To characterize the spatial intratumor heterogeneity of PD-L1...

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PMID: 38459590
DOI: 10.1093/jnci/djae053

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