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Comprehensive analysis of lactate-related gene profiles and immune characteristics in lupus nephritis

22 Feb 2024

Abstract excerpt

Objectives: The most frequent cause of kidney damage in systemic lupus erythematosus (SLE) is lupus nephritis (LN), which is also a significant risk factor for morbidity and mortality. Lactate metabolism and protein lactylation might be related to the development of LN. However, there is still a lack of relative research to prove the hypothesis. Hence, this study was conducted to screen the lactate-related...

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PMID: 38455045
DOI: 10.3389/fimmu.2024.1329009

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