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Article

Association between oxidative stress and chronic orofacial pain and potential druggable targets: Evidence from a Mendelian randomization study.

Journal of oral rehabilitation - 1 Jun 2024

Zhang Shao-Hui, Feng Yao, Zhong Meng-Mei, Xie Jia-Hao, Xu Wei

Abstract excerpt

BACKGROUND: Oxidative stress indicators affect chronic orofacial pain (COFP), but how to reduce these effects is uncertain. OBJECTIVES: 11 oxidative stress biomarkers were collected as exposures, while four forms of COFP were chosen as outcomes for Mendelian randomization (MR) study. METHODS: The effect estimates between oxidative stress and COFP were calculated using inverse variance-weighted MR (IVW-MR). Then,...

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PMID: 38414129
DOI: 10.1111/joor.13663

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