Article
A case of dMMR/MSI-H/TMB-H colon cancer with brain metastasis treated with PD-1 monoclonal antibody.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 15 Feb 2024
Xiang Tao, Zhang Hangyu, Fang Weijia, Chen Wenbin
Abstract excerpt
A 70-year-old man had radical surgery for colon cancer one year before the symptoms of memory loss and decreasing cognitive function. Subsequent magnetic resonance imaging revealed a brain mass, which was surgically resected and confirmed to be metastatic intestinal adenocarcinoma. Immunohistochemistry of the primary tumor and brain metastasis showed mismatch repair deficiency. The patient received adjuvant...
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