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miR-10b-5p-mediated upregulation of PIEZO1 predicts poor prognosis and links to purine metabolism in breast cancer

26 Mar 2022

Abstract excerpt

BACKGROUND: Increasing evidence has reported the critical roles of PIEZO1 in organism. However, the knowledge of PIEZO1 in human cancers is still inadequate. METHODS: In silico analyses and experimental validation were performed to analyze PIEZO1's expression, prognostic values and potential upstream/downstream mechanism in breast cancer. RESULTS: PIEZO1 was significantly overexpressed in human breast cancer cell...

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PMID: 35351580
DOI: 10.1016/j.ygeno.2022.110351

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