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Article

Kled: an ultra-fast and sensitive structural variant detection tool for long-read sequencing data.

Briefings in bioinformatics - 22 Jan 2024

Zhang Zhendong, Jiang Tao, Li Gaoyang, Cao Shuqi, Liu Yadong, Liu Bo, Wang Yadong

Abstract excerpt

Structural Variants (SVs) are a crucial type of genetic variant that can significantly impact phenotypes. Therefore, the identification of SVs is an essential part of modern genomic analysis. In this article, we present kled, an ultra-fast and sensitive SV caller for long-read sequencing data given the specially designed approach with a novel signature-merging algorithm, custom refinement strategies and a...

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Identifiers

PMID: 38385878
DOI: 10.1093/bib/bbae049
PMCID: PMC10883419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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