Article

NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data

2016-12-09

Abstract excerpt

<h4>Background</h4> Structural variants (SVs) in human genomes are implicated in a variety of human diseases. Long-read sequencing delivers much longer read lengths than short-read sequencing and may greatly improve SV detection. However, due to the relatively high cost of long-read sequencing, it is unclear what coverage is needed and how to optimally use the aligners and SV callers. <h4>Results</h4> In this st...

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Literature Corpus work: bb4b6f8b-375f-5efa-8551-03d49c79cceb
DOI: 10.1101/092544

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