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Article

POLR2A Mutation is a Poor Prognostic Marker of Cerebellopontine Angle Meningioma.

Neurosurgery - 1 Aug 2024

Okano Atsushi, Miyawaki Satoru, Teranishi Yu, Hongo Hiroki, Dofuku Shogo, Ohara Kenta, Sakai Yu, Shin Masahiro, Nakatomi Hirofumi, Saito Nobuhito

Abstract excerpt

BACKGROUND AND OBJECTIVES: Recent molecular analyses have shown that the driver genetic mutations of meningiomas were associated with the anatomic location. Among these, POLR2A mutation is common among lesions in the skull base, mainly in the cerebellopontine angle (CPA). The objective of this study was to investigate the efficacy of POLR2A mutation as a prognostic marker for CPA meningiomas. METHODS: We...

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Identifiers

PMID: 38380947
DOI: 10.1227/neu.0000000000002873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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