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Article

Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer

5 Feb 2024

Abstract excerpt

Background Colon cancer is a heterogeneous disease and consists of various molecular subtypes. Despite advances in high-throughput expression profiling, limitations remain in predicting clinical outcome and assigning specific treatment to individual cases. Tumor-immune interactions play a critical role, with tumors that activate the immune system having better outcome for the patient. The localization of T cells...

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PMID: 38375478
DOI: 10.3389/fimmu.2024.1293618

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