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Immune-related genes in tumor-specific CD4+ and CD8+ T cells in colon cancer

22 Jun 2020

Abstract excerpt

Abstract Background Immune escape is an immunological mechanism underlying tumorigenesis, and T cells play an important role in this process. In this study, immune-related genes were evaluated in tumor-infiltrating CD4+and CD8+T cells in colon cancer. Methods ESTIMATE was used to calculate stromal and immune scores for tumor datasets downloaded from The Cancer Genome Atlas–Colon Cancer (COAD). Differentially...

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PMID: 32571262
DOI: 10.1186/s12885-020-07075-x

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