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Article

An inflamed tumor cell subpopulation promotes chemotherapy resistance in triple negative breast cancer.

Scientific reports - 14 Feb 2024

Jacobo Jacobo Mauricio, Donnella Hayley J, Sobti Sushil, Kaushik Swati, Goga Andrei, Bandyopadhyay Sourav

Abstract excerpt

Individual cancers are composed of heterogeneous tumor cells with distinct phenotypes and genotypes, with triple negative breast cancers (TNBC) demonstrating the most heterogeneity among breast cancer types. Variability in transcriptional phenotypes could meaningfully limit the efficacy of monotherapies and fuel drug resistance, although to an unknown extent. To determine if transcriptional differences between...

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Identifiers

PMID: 38355954
DOI: 10.1038/s41598-024-53999-w
PMCID: PMC10866903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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