Article
Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales.
Nature communications - 14 Feb 2024
White Rhys T, Bull Matthew J, Barker Clare R, Arnott Julie M, Wootton Mandy, Jones Lim S, Howe Robin A, Morgan Mari, Ashcroft Melinda M, Forde Brian M, Connor Thomas R, Beatson Scott A
Abstract excerpt
Antibiotic resistance is a significant global public health concern. Uropathogenic Escherichia coli sequence type (ST)131, a widely prevalent multidrug-resistant clone, is frequently associated with bacteraemia. This study investigates third-generation cephalosporin resistance in bloodstream infections caused by E. coli ST131. From 2013-2014 blood culture surveillance in Wales, 142 E. coli ST131 genomes were...
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