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Article

TB-DROP: deep learning-based drug resistance prediction of Mycobacterium tuberculosis utilizing whole genome mutations.

BMC genomics - 12 Feb 2024

Wang Yu, Jiang Zhonghua, Liang Pengkuan, Liu Zhuochong, Cai Haoyang, Sun Qun

Abstract excerpt

The most widely practiced strategy for constructing the deep learning (DL) prediction model for drug resistance of Mycobacterium tuberculosis (MTB) involves the adoption of ready-made and state-of-the-art architectures usually proposed for non-biological problems. However, the ultimate goal is to construct a customized model for predicting the drug resistance of MTB and eventually for the biological phenotypes...

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Identifiers

PMID: 38347478
DOI: 10.1186/s12864-024-10066-y
PMCID: PMC10860279

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