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Article

An explainable machine learning platform for pyrazinamide resistance prediction and genetic feature identification of Mycobacterium tuberculosis.

Journal of the American Medical Informatics Association : JAMIA - 1 Mar 2021

Zhang Andrew, Teng Ling, Alterovitz Gil

Abstract excerpt

OBJECTIVE: Tuberculosis is the leading cause of death from a single infectious agent. The emergence of antimicrobial resistant Mycobacterium tuberculosis strains makes the problem more severe. Pyrazinamide (PZA) is an important component for short-course treatment regimens and first- and second-line treatment regimens. This research aims for fast diagnosis of M. tuberculosis resistance to PZA and identification...

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Share to Antitubercular Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Machine Learning

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Share to Neural Networks, Computer

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Source

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Identifiers

PMID: 33215194
DOI: 10.1093/jamia/ocaa233
PMCID: PMC7936518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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