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Article

The Fibroblast Landscape in Stomach Carcinogenesis

1 Jan 2024

Abstract excerpt

Numerous recent studies using single cell RNA sequencing and spatial transcriptomics have shown the vast cell heterogeneity, including epithelial, immune, and stromal cells, present in the normal human stomach and at different stages of gastric carcinogenesis. Fibroblasts within the metaplastic and dysplastic mucosal stroma represent key contributors to the carcinogenic microenvironment in the stomach. The...

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PMID: 38342299
DOI: 10.1016/j.jcmgh.2024.02.001

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