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Article

A novel three-dimensional Nrf2 reporter epidermis model for skin sensitization assessment

9 Feb 2024

Abstract excerpt

Skin sensitization assessment has progressed from the use of animal models towards the application of New Approach Methodologies (NAMs). Several skin sensitization NAMs are accepted for regulatory use, but a majority relies on submerged in vitro cell cultures that limit their applicability domain, posing challenges for testing hydrophobic chemicals and mixtures. A newly developed three-dimensional (3D) Nrf2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38341018
DOI: 10.1016/j.tox.2024.153743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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