Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and validation of KIF23 as a hypoxia-regulated lactate metabolism-related oncogene in uterine corpus endometrial carcinoma.

Life sciences - 15 Mar 2024

Wang Tao, Peng Xiaotong, Liu Wenwen, Ji Mei, Sun Jing

Abstract excerpt

AIMS: The "Warburg effect" has been developed from the discovery that hypoxia-inducible factor 1α (HIF-1α) could promote the conversion of pyruvate to lactate. However, no studies have linked hypoxia and lactate metabolism to uterine corpus endometrial carcinoma (UCEC). MAIN METHODS: Sequencing and clinical data of patients with UCEC were extracted from The Cancer Genome Atlas (TCGA) database. Hypoxia-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometrial Neoplasms
Share to Hypoxia
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Microtubule-Associated Proteins

Share to Mutation

Share to Oncogenes

Share to Tumor Microenvironment

Source

Identifiers

PMID: 38336274
DOI: 10.1016/j.lfs.2024.122490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and validation of KIF23 as a hypoxia-regulated lactate metabolism-related oncogene in uterine corpus endometrial carcinoma.PMID 38336274Read ↗

Lactate metabolism-related genes to predict the clinical outcome and molecular characteristics of endometrial cancerSemantic proximity Read ↗

Comprehensive Analysis of the Glycolysis-Related Gene Prognostic Signature and Immune Infiltration in Endometrial CancerSemantic proximity Read ↗

Lipid-Metabolism-Related Gene Signature Predicts Prognosis and Immune Microenvironment Alterations in Endometrial CancerSemantic proximity Read ↗

A novel lactate metabolism-related signature predicts prognosis and tumor immune microenvironment of breast cancerSemantic proximity Read ↗

Single-cell transcriptome analysis revealed heterogeneity in glycolysis and identified IGF2 as a therapeutic target for ovarian cancer subtypesSemantic proximity Read ↗

MiRNA based tumor mutation burden diagnostic and prognostic prediction models for endometrial cancer.Semantic proximity Read ↗

Identification of KIF23 as a prognostic signature for ovarian cancer based on large scale samples and clinical validationSemantic proximity Read ↗

Lactylation drives tumor microenvironment remodeling and immune evasion in esophageal cancer revealed by multiomics and single cell transcriptomicsSemantic proximity Read ↗

Metabolism-associated molecular classification of uterine corpus endometrial carcinomaSemantic proximity Read ↗

Construction of a prognostic signature for serous ovarian cancer based on lactate metabolism-related genesSemantic proximity Read ↗

Lactate-related gene signatures predict prognosis and immune profiles in esophageal squamous cell carcinomaSemantic proximity Read ↗

Lactate dehydrogenase A is a diagnostic biomarker associated with immune infiltration, m6A modification and ferroptosis in endometrial cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.