Article
Cluster analysis to identify long COVID phenotypes using 129Xe magnetic resonance imaging: a multicentre evaluation.
The European respiratory journal - 1 Mar 2024
Eddy Rachel L, Mummy David, Zhang Shuo, Dai Haoran, Bechtel Aryil, Schmidt Alexandra, Frizzell Bradie, Gerayeli Firoozeh V, Leipsic Jonathon A, Leung Janice M, Driehuys Bastiaan, Que Loretta G, Castro Mario, Sin Don D, Niedbalski Peter J
Abstract excerpt
BACKGROUND: Long COVID impacts ∼10% of people diagnosed with coronavirus disease 2019 (COVID-19), yet the pathophysiology driving ongoing symptoms is poorly understood. We hypothesised that 129Xe magnetic resonance imaging (MRI) could identify unique pulmonary phenotypic subgroups of long COVID. Therefore, we evaluated ventilation and gas exchange measurements with cluster analysis to generate imaging-based...
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