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Association analysis of the IKZF4 gene with Alopecia Areata in the Chinese Han population.

Alternative therapies in health and medicine - 1 Oct 2024

Miao Ying, Qi Sisi, Hu Ruiming, Sheng Youyu, Yang Qinping

Abstract excerpt

Objective: The IKZF4(Ikaros family zinc finger 4) gene encodes Eos, a zinc finger transcription factor that belongs to the Ikaros family. High expression of Eos on Treg cells is important for the suppression of autoimmune responses and immune homeostasis. It has been suggested that the SNP in IKZF4 may influence the pathogenesis of AA(alopecia areata). The purpose of this study was to explore the relationship...

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PMID: 38330583

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