Article
HLA class I expression on human platelets is highly variable and correlates with distinct allele group frequencies.
Blood transfusion = Trasfusione del sangue - 1 Sept 2024
Cantisani Rocco, Del Re Valeria, Toraldo Francesca, Cantara Silvia, Pozzessere Simone, Marotta Giuseppe, Spreafico Adriano
Abstract excerpt
BACKGROUND: Human leukocyte antigen (HLA) class I molecules are expressed on platelets and can represent a source of alloimmunization in recipients of platelet transfusions. HLA mismatch between donors and recipients may be associated with the induction of anti-HLA antibodies, which can culminate in refractoriness to platelet transfusions. In the present study we analyzed HLA allele group frequencies and HLA...
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