Article
Utility of fluorescence in situ hybridization for ploidy and p57 immunostaining in discriminating hydatidiform moles.
Biochemical and biophysical research communications - 4 Apr 2014
Chen Kuang-Hua, Hsu Sheng-Chi, Chen Hou-Yu, Ng Kwai-Fong, Chen Tse-Ching
Abstract excerpt
Discrimination between complete moles (CMs), partial moles (PMs), and hydropic abortions (HAs) is important as the risk of persistent gestational trophoblastic disease (GTD) differs for each condition. We evaluated whether ancillary fluorescence in situ hybridization (FISH) with a set of chromosome enumeration probes (CEP) for chromosomes X, Y, and 17 and p57 immunostaining could improve the clinical diagnosis....
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