Article
A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome.
Communications biology - 30 Jan 2024
Liu Xiaomin, Tong Xin, Zou Leying, Ju Yanmei, Liu Mingliang, Han Mo, Lu Haorong, Yang Huanming, Wang Jian, Zong Yang, Liu Weibin, Xu Xun, Jin Xin, Xiao Liang, Jia Huijue, Guo Ruijin, Zhang Tao
Abstract excerpt
The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. Here, by dissecting the human genome and nasal metagenome data from 1401 healthy individuals, we demonstrated that the top three host genetic principal components strongly correlated with the nasal microbiota...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.