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Article

The genetic and immune features of salivary gland secretory carcinoma with high-grade transformation.

Oral diseases - 1 Oct 2024

Wang Yu, Sun Jingjing, Sun Bao, Zhang Chunye, Tian Zhen, Wang Lizhen, Li Jiang

Abstract excerpt

OBJECTIVES: To compare the clinicopathological, molecular, and immune features of conventional and high-grade transformation (HGT) secretory carcinoma (SC) in salivary glands. MATERIALS AND METHODS: The clinicopathological data of 88 cases including 74 conventional SCs and 14 SCs with HGT were reviewed. Targeted next-generation sequencing was performed in 11 SCs with HGT and 7 conventional SCs. The level of PD-L1...

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PMID: 38263601
DOI: 10.1111/odi.14876

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