Article
Mammary analogue secretory carcinoma of salivary glands with high-grade transformation: report of 3 cases with the ETV6-NTRK3 gene fusion and analysis of TP53, β-catenin, EGFR, and CCND1 genes.
The American journal of surgical pathology - 1 Jan 2014
Skálová Alena, Vanecek Tomas, Majewska Hanna, Laco Jan, Grossmann Petr, Simpson Roderick H W, Hauer Lukas, Andrle Pavel, Hosticka Lubor, Branžovský Jindrich, Michal Michal
Abstract excerpt
Mammary analogue secretory carcinoma of salivary gland origin (MASC) is a recently described tumor resembling secretory carcinoma of the breast characterized by strong S-100 protein, mammaglobin, and vimentin immunoexpression and which harbors a t(12;15) (p13;q25) translocation resulting in ETV6-NTRK3 fusion product. Histologically, conventional MASC displays bland histomorphology and a lobulated growth pattern...
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