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Article

Idiopathic Epilepsy Risk Allele Trends in Belgian Tervuren: A Longitudinal Genetic Analysis.

Genes - 18 Jan 2024

Kinsey Nathan, Belanger Janelle M, Mandigers Paul J J, Leegwater Peter A, Heinonen Tiina, Hytönen Marjo K, Lohi Hannes, Ostrander Elaine A, Oberbauer Anita M

Abstract excerpt

Idiopathic epilepsy (IE) has been known to be inherited in the Belgian Tervuren for many decades. Risk genotypes for IE in this breed have recently been identified on Canis familiaris chromosomes (CFA) 14 and 37. In the current study, the allele frequencies of these loci were analyzed to determine whether dog breeders had employed a purposeful selection against IE, leading to a reduction in risk-associated allele...

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Identifiers

PMID: 38255002
DOI: 10.3390/genes15010114
PMCID: PMC10815166

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