Article
Identification of Genetic Variants for Diabetic Retinopathy Risk Applying Exome Sequencing in Extreme Phenotypes.
BioMed research international - 1 Jan 2024
Zenteno Juan C, Chacón-Camacho Oscar F, Ordoñez-Labastida Vianey, Miranda-Duarte Antonio, Del Castillo Camila, Nava Jessica, Mendoza Fatima, Montes-Almanza Luis, Mora-Roldán Germán, Gazarian Karlen
Abstract excerpt
Background: Diabetic retinopathy (DR) risk has been shown to vary depending on ethnic backgrounds, and thus, it is worthy that underrepresented populations are analyzed for the potential identification of DR-associated genetic variants. We conducted a case-control study for the identification of DR-risk variants in Mexican population. Methods: We ascertained 60 type 2 diabetes mellitus (T2DM) patients. Cases (n =...
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