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Genetic polymorphism and clustering of the Plasmodium cynomolgi Duffy binding protein 1 region II of recent macaque isolates from Peninsular Malaysia.

Parasitology research - 19 Jan 2024

Latif Eira Nurfarisha Mohd, Noordin Naqib Rafieqin, Shahari Shahhaziq, Amir Amirah, Lau Yee-Ling, Cheong Fei-Wen, Abdullah Mohd Lutfi, Fong Mun Yik

Abstract excerpt

Plasmodium cynomolgi is a simian malaria parasite that has been increasingly infecting humans. It is naturally present in the long-tailed and pig-tailed macaques in Southeast Asia. The P. cynomolgi Duffy binding protein 1 region II [PcDBP1(II)] plays an essential role in the invasion of the parasite into host erythrocytes. This study investigated the genetic polymorphism, natural selection and haplotype...

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PMID: 38240877
DOI: 10.1007/s00436-024-08125-0

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