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Article

Validation of genes for H-ARS severity prediction in leukemia patients - interspecies comparison, challenges, and promises

16 Jan 2024

Abstract excerpt

Purpose In a previous baboon-study, a total of 29 genes were identified for clinical outcome prediction of the hematologic, acute, radiation, syndrome (H-ARS) severity. Among them, four genes (FDXR, DDB2, POU2AF1, WNT3) appeared promising and were validated in five leukemia patients. Within this study, we sought further in-vivo validation in a larger number of whole-body irradiated patients.Material and Methods...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38227483
DOI: 10.1080/09553002.2023.2295295

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