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Article

Impact of Inter-Individual Variance in the Expression of a Radiation-Responsive Gene Panel Used for Triage

20 Jun 2018

Abstract excerpt

In previous studies we determined a gene expression signature in baboons for predicting the severity of hematological acute radiation syndrome. We subsequently validated a set of eight of these genes in leukemia patients undergoing total-body irradiation. In the current study, we addressed the effect of intra-individual variability on the basal level of expression of those eight radiation-responsive genes...

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PMID: 29923790
DOI: 10.1667/rr15013.1

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