Article
Causal association of gastroesophageal reflux disease with chronic sinusitis and chronic disease of the tonsils and adenoids.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Jun 2024
Li Weizhen, Zhang Yanan, Li Xinwei, Xie Mengtong, Dong Lin, Jin Mengdi, Lu Qingxing, Zhang Min, Xue Fengyu, Jiang Lintong, Yu Qiong
Abstract excerpt
BACKGROUND: Exploring bidirectional causal associations between gastroesophageal reflux disease (GERD) and chronic disease of the tonsils and adenoids and chronic sinusitis, respectively. METHODS: We first conducted a TSMR (two-sample mendelian randomization) study using the results of the inverse variance weighting method as the primary basis and bidirectional MR to rule out reverse causation. Subsequently, MVMR...
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