DNI-MDCAP: improvement of causal MiRNA-disease association prediction based on deep network imputation.

doi:10.1186/s12859-024-05644-6

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Article

DNI-MDCAP: improvement of causal MiRNA-disease association prediction based on deep network imputation.

BMC bioinformatics - 12 Jan 2024

Han Yu, Zhou Qiong, Liu Leibo, Li Jianwei, Zhou Yuan

Abstract excerpt

BACKGROUND: MiRNAs are involved in the occurrence and development of many diseases. Extensive literature studies have demonstrated that miRNA-disease associations are stratified and encompass ~ 20% causal associations. Computational models that predict causal miRNA-disease associations provide effective guidance in identifying novel interpretations of disease mechanisms and potential therapeutic targets. Although...

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PMID: 38216907
DOI: 10.1186/s12859-024-05644-6
PMCID: PMC10785389

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