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Article

LE-MDCAP: A Computational Model to Prioritize Causal miRNA-Disease Associations.

International journal of molecular sciences - 19 Dec 2021

Huang Zhou, Han Yu, Liu Leibo, Cui Qinghua, Zhou Yuan

Abstract excerpt

MicroRNAs (miRNAs) are associated with various complex human diseases and some miRNAs can be directly involved in the mechanisms of disease. Identifying disease-causative miRNAs can provide novel insight in disease pathogenesis from a miRNA perspective and facilitate disease treatment. To date, various computational models have been developed to predict general miRNA-disease associations, but few models are...

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Algorithms
Computer Simulation
Gene Expression Regulation
Genetic Association Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

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PMID: 34948403
DOI: 10.3390/ijms222413607
PMCID: PMC8706837

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