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Article

CTG18.1 expansion in transcription factor 4 (TCF4) in corneal graft failure: preliminary study.

Cell and tissue banking - 1 Jun 2024

Westin Ida Maria, Viberg Andreas, Golovleva Irina, Byström Berit

Abstract excerpt

Fuchs endothelial corneal dystrophy (FECD) is caused by a corneal endothelial cell loss, leading to corneal edema and visual impairment. The most significant genetic risk factor for FECD is an expansion of the CTG18.1 locus in transcription factor 4 (TCF4). The current treatment for severe FECD is corneal transplantation, with Descemet stripping automated keratoplasty (DSAEK) as a common surgical method. Although...

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Identifiers

PMID: 38206443
DOI: 10.1007/s10561-023-10123-y
PMCID: PMC11142935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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