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Article

Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections.

European journal of human genetics : EJHG - 1 Jun 2024

Adebamowo Sally N, Adeyemo Adebowale, Adebayo Amos, Achara Peter, Alabi Bunmi, Bakare Rasheed A, Famooto Ayotunde O, Obende Kayode, Offiong Richard, Olaniyan Olayinka, Ologun Sanni, Rotimi Charles, Adebamowo Clement A

Abstract excerpt

Genetic variants that underlie susceptibility to cervical high-risk human papillomavirus (hrHPV) infections are largely unknown. We conducted discovery genome-wide association studies (GWAS), replication, meta-analysis and colocalization, generated polygenic risk scores (PRS) and examined the association of classical HLA alleles and cervical hrHPV infections in a cohort of over 10,000 women. We identified...

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Source

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Identifiers

PMID: 38200081
DOI: 10.1038/s41431-023-01521-7
PMCID: PMC11153215

Genes

CDH12
LDB2
SMAD2
TPTE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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