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Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis

8 Jan 2024

Abstract excerpt

Staphylococcus aureus colonizes the nares of approximately 30% of humans, a risk factor for opportunistic infections. To gain insight into S. aureus virulence potential in the spaceflight environment, we analyzed RNA-Seq, cellular proteomics, and metabolomics data from the "Biological Research in Canisters-23" (BRIC-23) GeneLab spaceflight experiment, a mission designed to measure the response of S. aureus to...

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PMID: 38191486
DOI: 10.1038/s41526-023-00343-7

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