Investigation of simulated microgravity effects on Streptococcus mutans physiology and global gene expression

Abstract excerpt

Abstract Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight, host factors that could contribute to oral diseases such as caries and periodontitis. However, the specific physiological response of caries-causing bacteria such asStreptococcus mutansto space flight and/or ground-based simulated microgravity...

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